![]() In the entropy, delta S, if S2 is greater than S1, then S2 minus S1 wouldīe a positive value. And looking at our equation, if the number of microstates increases, then so does the entropy. Of possible positions for the gas particles. When the volume is doubled, that increases the number Next, let's think about what happens to the number of available microstates when the volume is doubled. Therefore, the initial temperature, T1, is equal to the final temperature, T2. During the expansion of the gas, the temperature is kept constant. ![]() Mole of our ideal gas and n2 is also equal to one mole. Volume for the final volume, therefore, V2, or the final volume, is equal to 2 times V1. So if the initial volume is V1, let's say we have twice the And now our gas particlesĪre free to travel around in a larger volume. Let's say we go aheadĪnd remove the divider. Particles, in a container, and the container has a removable divider separating the container One mole of an ideal gas, so here are the gas In our first situation, we're starting off with The change in entropy for a number of different situations. Of either matter or energy, that really relates to a decrease in the number of available microstates, which means a decrease in And if we think about aĭecrease in the disorder of the system or an increase in the order, or a decrease in the dispersal Terms as meaning an increase in the number of microstates and therefore an increase in ![]() However, when we're using the equationĭeveloped by Boltzmann, we should think about these Using the word microstates, people will describeĪn increase in entropy as an increase in disorder or an increase in the dispersal Microstates decreases, that represents a decrease Of a system increases, that represents an increase in entropy, and if the number of According to this equation, entropy, symbolized by S, is equal to Boltzmann's constant, k, times the natural log of W, and W represents the number Now that we understand theĬoncept of microstates, let's look at an equationĭeveloped by Boltzmann that relates entropy to Is a number that's too high for us to even comprehend. So the number of microstatesĪvailable to this system of one mole of gas particles Moving from one microstate into another, into another, into another. The microscopic level, we see that the system is So from a macroscopic point of view, nothing seems to change. A good way to think aboutĪ microstate would be like taking a picture of Microscopic arrangement of positions and energies So going back to our boxes,īox 1, box 2 and box 3, each box shows a different To the kinetic energies of the particles. With an ideal gas here, by energies, we're referring Microscopic arrangement of all of the positions andĮnergies of the gas particles. Of each particle is equal to 1/2 mv squared, where m is the mass of each ![]() Particles are meant to represent the velocities of the particles. And the magnitude and theĭirection give a velocity. However, when we put anĪrrow on each particle, that also gives us the direction. ![]() Of a particle tells us how fast the particle is traveling. Slightly different positions and the velocities might have changed. Particles in our system at one moment in time, in box 1, if we think about them atĪ different moment in time, in box 2, the particles might be in Slamming into each other and transferring energy from Slamming into the sides of the container and maybe Here in the first box, imagine these gas particles However, from a microscopic point of view, things are changing all of the time. So from a macroscopic point of view, nothing seems to be changing. Particles is at equilibrium, then the pressure, the volume, the number of moles, and the temperature all remain the same. Moles at a specific pressure, volume, and temperature. And to think about microstates, let's consider one mole of an ideal gas. Of entropy is related to the idea of microstates. ![]()
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![]() ![]() Select Programs and Features or Uninstall a Program.You can also easily access this by typing "Control Panel" in your Windows Start menu. Then, uninstall QuickBooks Deskop by following these steps below: You can get all of this info from your account management portal. Please also remember to have your license number handy and write down your product, year and version. Remember, doing clean install won’t affect your company data.įirst, let's make sure to gather your information and back up your data to save your work. Thanks for the additional information, can try to completely uninstall then reinstall the QuickBooks software to fix company file issues. Let me know how it goes and I'll get back to help you some more. ![]() If you're still having the same result after the steps above, you'll want to open manually open the company file on a remote computer. Here's also an article for reference: QuickBooks Desktop Users and Restrictions. If the user is still not able to open the company file in the new location, we can delete their access and add them again. To view the other solutions, you can check this article: Company file is missing or cannot be found. If you see a reply for each packet, this means your computer is connected to your network. If it's a packet loss or a slow reply, I'd recommend consulting your IT professional to diagnose your network.
![]() ![]() Gorringes recommend Mailboxes and Alban Shipping for high value or delicate items. ASPHALT GLSSWR TBLE KTCHN NES MCH MO LAMP CHIMNEYS LANTERN GLOBES POTTERY. Exterior Details Style Traditional Construction Brick Built In 2008 Stories 2 Parking Attached - Side, Circular Driveway Garage Bays 4 Features Garage Door Opener, Gas Grill Sewer Public Sewer Acres 1. ![]() However all packing will be at the purchaser’s risk. 00 CORSETS BRASSIERS ETC EX RUB 54581 547400 571500 502200. Insurance can be arranged subject to the terms of the carriers. 707 Brass Lantern Pl, Brentwood, TN 37027 is a Single Family, Residential property listed for 3,400,000 The property is 9166 sq. Simply log in to your account and access contact information for all your weichert associates in one place. Postage and packing can be arranged by the Auctioneers and will be charged at cost of postage/delivery plus an minimum charge of £10 for the first Lot and £2 for each additional lot larger items may attract a higher fee Lot. 707 Brass Lantern Pl Brentwood TN 37027 . The Brass Lantern Restaurant and Lounge, Crossville: See 281 unbiased reviews of The Brass Lantern Restaurant and Lounge, rated 4 of 5 on Tripadvisor and ranked 22 of 105 restaurants in Crossville. 4 baths Lot: 1. ![]() Sale Results: Results from this sale will be available from the office and during the sale from our web site. 707 Brass Lantern Pl, Brentwood, TN 37027-6212. ![]() The specialists in charge of this auction will be available for consultation during the view days and will be happy to talk to you if you have any queries regarding any of the lots in the sale. Most of the 1900 to 1920s homes are listed on the National Historic Register of Places and the residents asked for an architecturally appropriate column. 209 208 DISNEY MADRIS HELWIG CAMEO AV AV B 707 706 306 708 HIGHDALE ST. They are posted in the viewing galleries and are announced by the Auctioneer. WAY COBBLE STONE RD BRASS LANTERN DR 3 GRAYVILLE SUMMERSH COBBLESTONE BRASS. Request additional information, schedule a showing, save to your property organizer. Get complete property information, maps, street view, schools, walk score and more. The Amenities were wonderful- a clean relaxing hot tub, cookies and tea in the afternoon, and the most delicious breakfast (get George’s blueberry sauce on your waffle, you will never taste anything better)! We really appreciated the effort of every little detail put into this Inn, including the sleds out back which we had a blast with, the chocolates at the bedside, and the environmentally friendly soap dispensers/choice of towel reuse.nGeorge and Mary Ann, we can’t wait to come back soonn-Brady & EvelynnP.S.Saleroom Notices: Saleroom notices amend the details on a lot after our catalogue has gone to press. Photos and Property Details for 707 BRASS LANTERN PL, BRENTWOOD, TN 37027. Find contact info for current and past residents, property value, and more. My boyfriend and I decided to stay here for a “staycation” during Covid and we feel as though we hit the jackpot! We absolutely loved our stay at the brass lantern, the room was cozy and clean, and the living room and inn it’s self were so cozy and homey! We absolutely adored the owners Mary Ann and George, who are we throughly enjoyed chatting with. In our Outlet (situated in Noth of Italy) we stock standard aluminium bars and all the non ferrous metals. Find people by address using reverse address lookup for 707 Brass Lantern Pl, Brentwood, TN 37027. ![]() ![]() ![]() I could still save the game, but I tweaked this while in the menu. I urge people not to tweak the inventory outside the limitations the game has (don't give yourself items you shouldn't have and don't tweak quantities above the number the game actually allows!) I'm not 100% sure but I'm trying to pinpoint what caused it and I know I gave myself some items in the 50s in regards to quantity. I confirmed that this issue also saves so restarting the game doesn't help - essentially I have to start from scratch now, which is a pain. Also, if you tweak the inventory with this table too much, the X button stops working at some point (open digivice menu) and you can't save, set skills, anything anymore. The guy had to have had another problem, I noticed the table gets an error if you hook it when you're not in your loaded save yet. Thanks for your work!ĮDIT: This table works today, on Citra Canary 1970 so I guess it's not really version bound as stated above. I've been looking for something to help me control my digimon, this table is perfect. The first match should be from the exe anyway. PS: I was too lazy to write code to only scan for the process memory region but it doesn't matter. Heck, the thing is that this AOB actually gives 3 matches because some other dlls have the same pattern so it definitely means you didn't use the right version. I don't expect that part of the code to change in the near future though. Other ones may work depending on how the compiler changes the usage of those registers. You must use 1675 nightly for absolute guarentee. It means your version doesn't match mine and has some weird code pattern. If it still gives you this error after attaching, it means that that AOB pattern is not found. Of course it gives this error when not attached. Then after i attach citra it gave same error.īut the strange thing it give error directly after i open the engine. and added some stuff to give error messages when not attached :facepalm: always forget that not everyone understands how things work behind the scene.ĭigimondecode.CT (44.36 KiB) Downloaded 479 timesīro i am already using nighty but this error come directly after i open the engine before i attach it to the citra. to enable script before loading the game, and item list for items from psp gameĮDIT5:added some more items. I don't plan to find those flags myself so you will have to do it yourself.ĮDIT3: AOB to find s_instance pointer instead to avoid the req. ![]() I think some ultimates are locked until you finish certain story events. Just remember to also change the other stats to fulfill the requirements. I haven't tried changing digimon id for evolving to a particular digimon but you can try changing the id to some champions that can evolve to a particular digimon that you want. You can now set evolution time to 0 to evolve early and many other things like changing lifespan. ![]() Not tested the aob with other versions of the EMU Shouldn't be far from the items.ĮDIT: forgot to attach table, this works for nightly 1675. Skill should be easy if you can find the addresses. The paging table is accessed through +18]. XXX YYY and you want the XXX) of the virtual address, then multiplying by 8 and adding to the paging table base address to obtain the memory base. The paging pointer works at the moment by masking the the 12 bits of the 12 bits to the left (eg. The System::Memory() function address scanner should work with other games too. Not what you want but here is an item ID/count, money editor. ![]() ![]() ![]() Store: Desperados 3 PS4 Arabic CUSA11112 – EUR If you use everyone’s guns in conjunction, you can eliminate large groups of guards, so be sure to use them whenever you need to.Downlaod Desperados 3 Arabic CUSA11112 – EUR Direct Links Downlaod Desperados 3 PS4 Arabic CUSA11112 – EUR Direct Links ABOUT GAME: ![]() For example, Cooper’s revolvers can shoot two people simultaneously, McCoy’s pistol is quiet and has range, and Hector’s shotgun can kill multiple people up close. Anyone within that blue circle will hear the gunshot, so use that to your advantage to plan things out. When you aim a gun, a blue circle appears around your character. You don’t want to give away your position with a gunshot, so make sure guards are out of earshot before you fire. They all serve different functions, but they all have one thing in common: they make a lot of noise. Still, Cooper and some of the other playable characters carry weapons with them, and they can be very powerful tools in the right hands. Don’t expect to take out dozens of guys with your revolvers and other guns. Be Smart with GunsĮven though Desperados III features some of the toughest gunslingers and cowpoke of the west, they’re not invincible. ![]() Just make sure you save before trying anything too fancy unless you want to get someone killed and lose some progress. Showdown Mode has a lot of potential, and you can execute some pretty awesome plans with it. Kate can throw perfume to stun onlooking guards so McCoy can snipe them with his pistol, for example. You can use any abilities you want in Showdown Mode, so you can even have some of your characters run interference to give the rest of the party some breathing room while they quietly kill some guards. This is perfect for double or triple takedowns, as each character can sneak up on their target and take them out together so no one gets spotted. Everyone can queue up one action, and when you press Execute Plan, they’ll carry them out simultaneously. By pressing the Shift key (or up on the d-pad on PS4/Xbox), you’ll freeze time and enter Showdown Mode, which allows you to plan your characters’ actions at the same time. Sometimes, you’ll need more than one person to execute your master plan, and that’s where Showdown Mode comes into play. You can turn it off or adjust the frequency, though, so it doesn’t get too annoying. You won’t be able to forget to save, either, as there’s a frequent save reminder pop up that flashes on screen every minute or so. ![]() Thankfully, there’s no penalty for saving as frequently as you’d like, so go ahead and quicksave like you’re about to murder a bunch of NPCs in a Bethesda game. Sometimes, you’ll just forget someone was standing there or you won’t have seen a guard hanging out behind a wall. Not only will making a habit of saving save you from the frustration of being set back further than you’d like, but it will also allow you to adjust to any unforeseen guards or enemies that throw a wrench into your plan. Any time you move a character forward, save. Anytime you kill a group of guards, save. Slip-ups and mistakes are inevitable in Desperados III, so you’ll want to make sure you save often so you don’t lose too much progress when things go wrong. ![]() ![]() ![]() Before this, Ryherd did a Meteorology Internship at WOI News from January 2016 to April 2017. Prior to KCRG Weather, Jan was a meteorologist at KOLN from May 2017 to August 2020. Later, she became a Pool Supervisor at the company from May 2013 to August 2014. After completing her school, Jan took her first job at the City of Webster City as an Assistant Swim Team Coach in January 2011. Meanwhile, Jan was also actively involved in Cy’s Eyes on the Skies, a weather broadcast at school, While working there, Ryherd was a producer and director during her school years. She was also an active member of the Central Iowa NWA chapter and student AMS chapter. She completed her BS in Meteorology and Journalism at Iowa State University from 2013 to 2017. Ryherd attended High School at Webster City from 2009 to 2013. She further enjoys the fact that the weather never bores her since it gives a different excitement every time. It was her younger days when Ryherd fell in love with the unstable weather. After a few days of her joining, the weather went crazy in Iowa, but that is what attracts her to be a meteorologist. She became a part of the KCRG Weather Team in August 2020. Jan Ryherd is a morning weather anchor and reporter at KCRG Weather who was born and brought up in Iowa. Jan Ryherd: Meteorologist at KCRG Weather From reading the weather data at KCRG Radar aka KCRG Pinpoint Doppler Radar to compiling a the station’s Weather forecast for the people of Cedar Rapids, the weather team has covered you all. They are experts in their field and handle the weather coverage efficiently. KCRG Weather team consists of meteorologists Joe Winters, Jan Ryherd, Kalie Pluchel, Kaj O’Mara, and Corey Thompson. Storms, Floods, Tornadoes, snow, severe weather, winter storms, are quite common in Cedar Rapids and it is KCRG Weather Team’s responsibility to report each and everything of weather in Iowa. Moreover, each member of the the channel’s News Team complies with the moral codes of journalism, treats everyone equally irrespective of gender, race, and ethnicity. Anchors closely work with the reporters and gather relevant information related to the hot topics. Besides, the channel’s News Team has extraordinary collaboration skills among the squad members. Not only do they keep an eye on regional affairs, but they also look for the state, national and international affairs. ![]() The team has qualified news anchors and reporters who have excellent research skills and a nose for sensing a good story. KCRG News Team includes Chris Earl, Jay Greene, Beth Malicki, Taylor Holt, Ethan Strin, Becky Phelps, and Brian Tabick. KCRG News TeamĪBC Cedar Rapids news team covers everything from Cedar Rapids local news to KCRG Weather, sports, and traffic. She still works at The Weather Channel as a full-time weather anchor. Britley, later, left Hearst Television too in March 2020 and joined The Weather Channel. She worked at KCRG Weather for more than 2 years and 11 months. KCRG Weather offers, Severe Weather, River Levels, KCRG Cancellations, Online Weather Academy, KCRG pinpoint Doppler Radar, Map Room, KCRG Closings, Freedom Festival, Cit圜AM Network, KCRG Weather Forcast, and WeatherCall.īritley Ritz stopped providing services to KCRG News in November 2017 after she found herself a better opportunity at Hearst Television as a full-time meteorologist. Moreover, it also focuses on Everyday Families, Show You Care, KCRG-TV9 Daily Digest, Gary DC Bureau, Locals Love Us, Latest Videos, PowerNation, Latest Newscasts, and Investigate TV. The station is a complete package of Cedar Rapids News, National/International News, KCRG Weather, sports transmission, KCRG 9.2, Election Results, and Student of the Month. KCRG News uses the brand name KCRG-TV 9 News and a catchphrase Your 24-Hour News (and weather) source. ![]() Moreover, viewers can also enjoy its services over-the-air on the antenna or at the official website. KCRG News comes on multiple local cables and satellites. Channel 9 News Cedar Rapids Iowa runs at Virtual CH 9 and serves the entire area of the Eastern Iowa TV market that includes Iowa City, Waterloo, Cedar Rapids, and Dubuque. KCRG News is a US-based TV channel owned by Gray Television and licensed to Cedar Rapids, Iowa. ![]() ![]() Whoever says the number 21 each round has to sit down. Please contact the Early Education Division to request. The next students in line says two and the counting continues around the circle. The content on the Web page you requested is currently under review. The creation of contrasts helps children to discover and experience the high and low, big and small, different shapes, different depths and different textures. The variety of shapes, forms, and textures are one of the kindergarten classroom design principles. Choose one student to begin counting aloud, saying the number one. Kindergarten is a preschool educational approach based on playing, singing, practical activities such as drawing, and social interaction as part of the. Kindergarten Classroom Design 2: Creation of Contrasts. Have students stand in a circle around the rug. Friedman, Nathaniel Hilger, Diane Whitmore. Education Home What Do Kids Learn in Kindergarten Whether physical, emotional or social, developing life skills is what kindergarten is all about. This game is a fun time filler for kindergarten that will help kids with counting skills. Browse 46,636 kindergarten class photo photos and images available, or search for kindergarten classroom to find more great photos and pictures. Through positive reinforcement, we focus on our classroom guidelines respecting others, and being responsible for ourselves.Ĭonferences are offered twice a year, but questions and concerns, and open dialogue are encouraged throughout the year. How Does Your Kindergarten Classroom Affect Your Earnings Evidence from Project STAR. The Owls class has a healthy balance of instruction time, and social / play time so our children are able to gain life skills such as working well with others, problem-solving, and conflict resolution. Moreover, a hands-on approach is used for Math and Science activities so learning becomes an immersive experience. ![]() ![]() The Owls class has a maximum ratio of 1-10, with two master-level certified teachers to ensure that each child receives the full benefit of this learning experience.īy implementing the Starfall learning program for reading and writing, we utilize creative and engaging activities including academicĬenters, journal writing, interactive charts, rhymes, computers, guided reading, and directive drawings to educate our children. ![]() ![]() They chew when nervous and will sometimes get nippy when fearful or under stress. They will often eat anything intended for them or not. Recognizing their personality and their tendencies play a big part in picking the right muzzle. As the experts at your pure-bred puppy point out, they are relentlessly curious. Beagles, although seen as happy go lucky and dogs ideal for people who live in apartments, were bred as hunting dogs. ![]() Because of this intended use, it can add to the tension of an already excitable atmosphere. Its purpose is to limit or restrict behavior. What to Look for In Picking Your Beagles MuzzleĪ muzzle is not a natural apparatus. Chewing, eating potentially dangerous things, excessively licking wounds, or playing too roughly can all be helped using a muzzle. Also, just because your dog is friendly does not mean they cannot benefit from wearing this accessory.ĭogs have many behaviors beyond biting a person or another animal in which they would benefit from wearing a muzzle. They are not merely used to prevent biting, nor does it mean that a dog wearing a muzzle has bitten someone. There are many reasons why a dog might need a muzzle. Understanding the use of muzzles first requires recognizing the incorrect assumptions about them and their use. The ease of putting it on, comfort, and the restrictions on behavior are factors to calculate before purchasing one for your pet. Therefore, a muzzle must not add to that condition. Every breed is different and so are their characteristics that need to be accounted for when picking a muzzle.īeagles are one breed that is prone to stress. However, protecting your pet from additional stress or the possibility of injury is trickier. Any muzzle that prevents a dog from biting will accomplish that end. When we see those happy faces, the first word that comes to mind is “lovable.” They greet everyone with a wag of the tail and enthusiasm that displays how excited they are at the possibility of making a new friend.Ī muzzle has two purposes, to protect people and protect your pet.
![]() ![]() "Averaged" means the weight adjustments are averaged over the number of iterations. During training, the tagger guesses a tag and adjusts weights according to whether or not the guess was correct. This basically means that it has a dictionary of weights associated with features, which it uses to predict the correct tag for a given set of features. TL DR: PerceptronTagger is a greedy averaged perceptron tagger. Currently I am using this code en spacy.load ('encorewebmd') possent 'lib/lzma.py this module provides classes and convenience functions for compressing and decompressing data using the lzma compression algorithm. ![]() I am using spacy and I want to get pos of the tokens in sentence. The documentation links to this blog post which does a good job of describing the theory. 1 I am working on a chatbot project using NLP. ![]() This is trained and tested on the Wall Street Journal corpus.Īlternatively, you can instantiate a PerceptronTagger and train its model yourself by providing tagged examples, e.g.: tagger = PerceptronTagger(load=False) # don't load existing model This is a pickled model that NLTK distributes, file located at: taggers/averaged_perceptron_tagger/averaged_perceptron_tagger.pickle. But I am unable to find a logic to assign POS tags for the bi-grams generated in Python. The NLTK library provides an easy-to-use postag function that takes a text as input and returns the part-of-speech of each token in. This will call PerceptronTagger's default constructor, which uses a "pretrained" model. As I have come across in Python, POS Tagging and creation of bi-grams can be done using NLTK or TextBlob package. To use the tagger you can simply call pos_tag(tokens). Here is the documentation for PerceptronTagger and here is the source code. According to the source code, pos_tag uses NLTK's currently reccomended POS tagger, which is PerceptronTagger as of 2018. ![]() ![]() ![]() In this work, we address the rapid selection of optimal resins for integrated chromatographic separations by proposing the use of mathematical programming techniques. It is critical to use a systematic approach to select promising resins for integrated chromatographic separations. Thus, the best resin for one separation step may not be the best choice when the whole sequence is considered, since performance is also related to the resins used at the other steps in the chromatographic sequence, their operating conditions and performance. ![]() However, in practice at industrial scale, a chromatography sequence, with two to four chromatographic separation steps, is usually implemented. Each microscale experiment is capable of being implemented for only a single resin, and hence the optimal resin is only the best one for the specific conditions tested in that experiment. To deal with the substantial volume of data generated from such microscale HTS experiments, rapid analysis using a systematic methodology to focus on the conditions that result in optimal overall process performance can become therefore critical.Īn additional concern is that current HTS methods optimize a chromatographic step irrespective of the rest of the chromatographic steps. 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 In HTS, the combination of robotic methods, parallel processing, and the miniaturization of bioprocess unit operations allows for a large number of potential process parameters to be examined within a short time, and also results in the generation of large amounts of data for evaluation. 1 Platforms that have a capacity for high‐throughput screening (HTS) are commonly used to identify the most promising candidates for further investigation, in terms of key criteria of large scale purification, like yield, purity, and productivity. In the early stages of purification process development, different types of resins need to be tested at small scale (1.5–5000 µL) under various operating conditions, including different pH values, salt concentrations, and flow rates, to establish the resin most suited for process application at large scale. on behalf of American Institute of Chemical Engineers Biotechnol. © 2017 The Authors Biotechnology Progress published by Wiley Periodicals, Inc. The computational results show the advantage of the proposed framework in terms of computational efficiency and flexibility. The proposed framework is successfully applied to an industrial case study of a process to purify recombinant Fc Fusion protein from low molecular weight and high molecular weight product related impurities, involving two chromatographic steps with eight and three candidate resins for each step, respectively. Dinkelbach's algorithm is used to solve the resulting mixed integer linear fractional programming model. A multiobjective mixed integer nonlinear programming model is developed and solved using the ε‐constraint method. An optimization‐based decision support framework is proposed to process the data generated from microscale experiments to identify the best resins to maximize key performance metrics for a biopharmaceutical manufacturing process, such as yield and purity. ![]() This method enabled > 90 % overall recovery of unformulated DS at ≥ 150 g/L.This work addresses rapid resin selection for integrated chromatographic separations when conducted as part of a high‐throughput screening exercise during the early stages of purification process development. Most of the rinse was combined with the retentate to hit the target protein concentration. After the retentate was collected, a minimal volume of buffer was added for the UF rinse. During the UF/DF process, the antibody was initially concentrated to 90 g/L, diafiltered, and concentrated to ≥ 180 g/L, then the retentate was collected. Analysis showed that the Capto S run removed the excipients with yields of ≥ 96%. ![]() In addition, Capto S has lower resin costs, takes less time to process, and uses milder elution conditions. A Capto S column was chosen over Protein A chromatography to remove excipients from formulated drug substance because of its higher binding capacity. Fortunately, a sufficient supply of formulated DS was available for reprocessing. Since the pilot plants were not available for large-scale campaigns, a creative alternative was needed to produce 2 kg of antibody from formulated DS for these studies. During process scale-up, the project team decided to make a high-concentration mAb drug substance for subcutaneous injection and change the formulation. The scope of this work is two-fold: 1) excipients removal from formulated mAb drug substance by Capto S chromatography and 2) UF/DF process development to make high-concentration drug substance (DS) for subcutaneous injection. ![]() |
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